Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 5/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148245 | 0.81 | CYP17A1 (0.37) | CYP17A1CDC25B | |
| SCHEMBL24783468 | 0.76 | CYP17A1 (0.33) | CYP17A1 | |
| SCHEMBL3018205 | 0.71 | KMT2A (0.39) | — | |
| SCHEMBL25226442 | 0.71 | APLNR (0.35) | — | |
| SCHEMBL21046903 | 0.69 | TRPV4 (0.38) | — | |
| SCHEMBL29837763 | 0.68 | TRPV4 (0.44) | — | |
| SCHEMBL26694042 | 0.68 | TRPV4 (0.44) | — | |
| SCHEMBL1827106 | 0.68 | TRPV4 (0.51) | — | |
| SCHEMBL29673491 | 0.68 | TRPV4 (0.51) | — | |
| SCHEMBL28574238 | 0.68 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643299-B1 | BIPYRIDINE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OR CONDITIONS | NOSCIRA SA (ES) | 2016-06-22 | — | — | EP | disclosed |