Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6622067 | 0.85 | PAOX (0.43) | PAOXSIGMAR1L3MBTL1TP53HTR7 | |
| SCHEMBL29993988 | 0.81 | HRH3 (0.40) | SIGMAR1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL13485582 | 0.79 | PAOX (0.39) | PAOXMC4RSIGMAR1RECQLCA1 | |
| SCHEMBL12015831 | 0.79 | PAOX (0.39) | PAOXMC4RLMNASIGMAR1RECQL | |
| SCHEMBL17102198 | 0.77 | CA2 (0.40) | PAOXMC4RLMNASIGMAR1CA1 | |
| SCHEMBL18803169 | 0.77 | PAOX (0.38) | PAOXMC4RSIGMAR1RECQLCA1 | |
| SCHEMBL3607141 | 0.77 | PAOX (0.42) | PAOXLMNACYP1A2L3MBTL1CA1 | |
| SCHEMBL731431 | 0.76 | KMT2A (0.51) | LMNACA1CA2CA9SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23753187 | 0.74 | KMT2A (0.50) | LMNACA1CA2CA9SMN1; SMN2 | |
| SCHEMBL13588746 | 0.74 | PAOX (0.36) | PAOXSIGMAR1L3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643299-B1 | BIPYRIDINE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OR CONDITIONS | NOSCIRA SA (ES) | 2016-06-22 | — | — | EP | disclosed |