SCHEMBL17850899

SCHEMBL17850899

O=C(c1cccc(-n2c3ccccc3c3ccccc32)c1)c1ccccc1C(=O)c1cccc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.50
KDM4E B2RXH2 2/20 0.50
ATM Q13315 2/20 0.50
ALDH1A1 P00352 2/20 0.47
FOLH1 Q04609 1/20 0.46
POLB P06746 4/20 0.45
AKR1C3 P42330 1/20 0.43
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KMT2A Q03164 2/20 0.42
MYC P01106 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
HSPA1A P0DMV8 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
NR4A1 P22736 1/20 0.42
PTPN7 P35236 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17851081 0.94 KDM4E (0.44) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL13781007 0.92 KDM4E (0.48) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL17851134 0.91 L3MBTL1 (0.55) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL13780976 0.90 L3MBTL1 (0.53) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL13780982 0.88 KDM4E (0.52) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL17850894 0.88 L3MBTL1 (0.52) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL13780969 0.88 L3MBTL1 (0.57) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL17851035 0.84 CNR2 (0.40) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL13780990 0.84 KDM4E (0.47) L3MBTL1KDM4EATMALDH1A1FOLH1
SCHEMBL17851141 0.84 KDM4E (0.47) L3MBTL1KDM4EATMALDH1A1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-3035401-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA L3MBTL1 251/4885KDM4E 2784/4885ATM 3303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.