SCHEMBL1785111

SCHEMBL1785111

CC(C)C(COC(=O)c1ccccc1)C(C)(OC(=O)c1ccccc1)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
ADRB2 P07550 5/20 0.51
ADRB1 P08588 5/20 0.51
ADRB3 P13945 5/20 0.51
CYP2D6 P10635 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
LMNA P02545 1/20 0.44
TDP1 Q9NUW8 4/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 3/20 0.42
SLC6A3 Q01959 2/20 0.42
HTR1A P08908 1/20 0.42
SCN1A P35498 1/20 0.42
SCN5A Q14524 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6948344 0.85 ALDH1A1 (0.54) ALDH1A1ADRB2ADRB1ADRB3CYP2D6
SCHEMBL28354348 0.81 CYP2D6 (0.54) ALDH1A1ADRB2ADRB1ADRB3CYP2D6
SCHEMBL561394 0.78 ALDH1A1 (0.60) ALDH1A1ADRB2ADRB1ADRB3CYP2D6
SCHEMBL14955016 0.77 ALDH1A1 (0.62) ALDH1A1ADRB2ADRB1ADRB3CYP2D6
Benzoic Acid SCHEMBL28286154 0.77 TSHR (0.50) ALDH1A1ADRB2ADRB1ADRB3CYP2D6
SCHEMBL27470899 0.75 ALDH1A1 (0.66) ALDH1A1ADRB2ADRB1ADRB3CYP2D6
SCHEMBL14956200 0.75 ALDH1A1 (0.65) ALDH1A1ADRB2ADRB1ADRB3MAPK1
SCHEMBL561495 0.75 ALDH1A1 (0.65) ALDH1A1ADRB2ADRB1ADRB3MAPK1
SCHEMBL1754909 0.75 ALDH1A1 (0.65) ALDH1A1ADRB2ADRB1ADRB3MAPK1
SCHEMBL571219 0.74 ALDH1A1 (0.69) ALDH1A1ADRB2ADRB1ADRB3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed