SCHEMBL17852141

SCHEMBL17852141

CCOC(=O)c1c(Br)cccc1-c1ccc2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.49
SLC6A4 P31645 2/20 0.49
SLC6A3 Q01959 2/20 0.49
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
LMNA P02545 2/20 0.47
GAA P10253 2/20 0.47
HPGD P15428 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GLA P06280 1/20 0.47
ATM Q13315 1/20 0.47
ALOX5 P09917 3/20 0.46
PTGS2 P35354 1/20 0.46
PTGES O14684 1/20 0.45
CCNC P24863 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30986126 0.85 SLC6A3 (0.63) SLC6A2SLC6A4SLC6A3KDM4ELMNA
SCHEMBL17852134 0.81 CDC25B (0.52) KDM4EALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL17852127 0.81 ALOX5 (0.51) KDM4EALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL17852149 0.77 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL11237854 0.77 CA12 (0.66) KDM4EALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL13776780 0.75 SLC6A3 (0.57) SLC6A2SLC6A4SLC6A3ALDH1A1MAPT
SCHEMBL8290711 0.75 PRKCZ (0.69) ALDH1A1MAPTGAAHPGDMEN1
SCHEMBL15505862 0.74 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL7179755 0.74 PLAU (0.53) SLC6A2SLC6A4SLC6A3HPGDSIRT2
SCHEMBL7452434 0.74 MEN1 (0.55) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160181542-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed
US-20160181542-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160181542-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME L1CAM, H1-10, H1-0 SLC6A2 4029/4885SLC6A4 4313/4885SLC6A3 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.