Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17852193 | 1.00 | TLR4 (0.52) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL16361993 | 0.94 | TLR4 (0.53) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL22381248 | 0.94 | TLR4 (0.53) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL19958445 | 0.88 | TLR4 (0.49) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL21944328 | 0.88 | TLR4 (0.49) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL17853226 | 0.88 | TLR4 (0.49) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL21943693 | 0.88 | TLR4 (0.49) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL16361991 | 0.88 | TLR4 (0.49) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL19961526 | 0.88 | TLR4 (0.49) | TLR4GAAPRKD3PRKCGPRKCB | |
| SCHEMBL16351450 | 0.88 | TLR4 (0.49) | TLR4GAAPRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160176909-A1 | REGIOSELECTIVE SILYL EXCHANGE OF PER-SILYLATED OLIGOSACCHARIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176909-A1 | REGIOSELECTIVE SILYL EXCHANGE OF PER-SILYLATED OLIGOSACCHARIDES | FUT6, SI, FUT5 | TLR4 3182/4885GAA 187/4885PRKD3 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.