SCHEMBL1785246

SCHEMBL1785246

CC(=O)CC(C)CCC(C)C

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
TDP1 Q9NUW8 2/20 0.57
CA1 P00915 3/20 0.39
BLM P54132 1/20 0.37
CA2 P00918 2/20 0.35
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
PTPN1 P18031 1/20 0.31
BHMT Q93088 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1786816 0.85 BLM (0.54) ALDH1A1TDP1CA1BLMLMNA
SCHEMBL15202976 0.83 BLM (0.57) ALDH1A1TDP1CA1BLMLMNA
SCHEMBL12713322 0.83 BLM (0.57) ALDH1A1TDP1CA1BLMLMNA
SCHEMBL17249627 0.83 BLM (0.57) ALDH1A1TDP1CA1BLMLMNA
SCHEMBL1784549 0.82 ALDH1A1 (0.48) ALDH1A1TDP1
SCHEMBL11764392 0.80 ALDH1A1 (0.46) ALDH1A1TDP1
SCHEMBL2612027 0.80 ALDH1A1 (0.65) ALDH1A1TDP1CA2LMNASMN1; SMN2
SCHEMBL20490003 0.79 CA1 (0.39) ALDH1A1TDP1CA1BLMCA2
SCHEMBL15062351 0.79 BHMT (0.47) ALDH1A1TDP1CA1BLMSLC1A3
SCHEMBL13891796 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368251-B Aromatic-based polyether amine alkoxylates 亨斯迈石油化学有限责任公司 2024-09-06 CN disclosed
US-20230233689-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins UNIV YALE (US) 2023-07-27 US disclosed
EP-3728541-B1 AROMATIC-BASED POLYETHERAMINE ALKOXYLATES HUNTSMAN PETROCHEMICAL LLC (US) 2023-05-10 EP disclosed
US-11603436-B2 Aromatic-based polyetheramine alkoxylates HUNTSMAN PETROCHEMICAL LLC (US) 2023-03-14 US disclosed
CN-115368251-A Aromatic-based polyetheramine alkoxylates 亨斯迈石油化学有限责任公司 2022-11-22 CN disclosed
CN-111492046-B Aromatic-based polyetheramine alkoxylates 亨斯迈石油化学有限责任公司 2022-09-09 CN disclosed
CN-113038834-B Benzhydrylated aromatic surfactants 银都拉玛投资氧化物有限责任公司 2022-07-22 CN disclosed
US-20220017444-A1 BENZHYDRYLATED AROMATIC SURFACTANTS INDORAMA VENTURES OXIDES LLC 2022-01-20 US disclosed
EP-3897142-A1 BENZHYDRYLATED AROMATIC SURFACTANTS Indorama Ventures Oxides LLC (US) 2021-10-27 EP disclosed
CN-113038834-A Diphenylmethylated aromatic surfactants 银都拉玛投资氧化物有限责任公司 2021-06-25 CN disclosed
US-6239090-B1 COMPOSITION USEFUL AS PAINT REMOVER, COMPRISING PROPYLENE CARBONATE, HYDROGEN PEROXIDE, WATER AND POLYVINYLPYRROLIDONE THICKENER HUNTSMAN PETROCHEMICAL CORPORATION 2001-05-29 US disclosed
US-6169061-B1 COMPRISING ALKYLENE CARBONATE, DIBASIC ESTER, HYDROGEN PEROXIDE, AND WATER HUNTSMAN PETROCHEMICAL CORPORATION 2001-01-02 US disclosed
WO-2000078875-A1 PAINT AND COATING REMOVER HUNTSMAN PETROCHEMICAL CORPORATION (US) 2000-12-28 WO disclosed
US-6162776-A Paint and coating remover HUNTSMAN PETROCHEMICAL CORPORATION (US) 2000-12-19 US disclosed
US-6159915-A Paint and coating remover HUNTSMAN PETROCHEMICAL CORPORATION (US) 2000-12-12 US disclosed
WO-2000063304-A1 PAINT AND COATING REMOVER HUNTSMAN PETROCHEMICAL CORPORATION (US) 2000-10-26 WO disclosed
US-6040284-A AN AQUEOUS MIXTURE FOR APPLYING TO A PAINTED SURFACE FOR A TIME AND UNDER CONDITIONS EFFECTIVE TO CAUSE BLISTERING OR BUBBLING OF THE PAINT, THEN STRIPPING THE PAINT OFF HUNTSMAN PETROCHEMICAL CORPORATION (US) 2000-03-21 US disclosed
EP-0983324-A1 PAINT AND COATING REMOVER HUNTSMAN PETROCHEMICAL CORPORATION (US) 2000-03-08 EP disclosed
WO-1998053016-A1 PAINT AND COATING REMOVER HUNTSMAN PETROCHEMICAL CORPORATION (US) 1998-11-26 WO disclosed
US-4021461-A INSECTICIDES ZOECON CORPORATION (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11603436-B2 Aromatic-based polyetheramine alkoxylates ALK, TYR, MITF ALDH1A1 3937/4885TDP1 3182/4885CA1 4578/4885
US-20230233689-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins ASGR1, LDLR, FCGR2A ALDH1A1 3256/4885TDP1 4559/4885CA1 3524/4885
US-20220017444-A1 BENZHYDRYLATED AROMATIC SURFACTANTS TYR, MITF, ALK ALDH1A1 2353/4885TDP1 3079/4885CA1 4398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.