SCHEMBL1785263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1786545	0.91	KDR (0.45)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1783816	0.88	KDR (0.46)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1787746	0.88	KDR (0.43)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1787441	0.87	KDR (0.42)	KMT2AKDRLMNASMN1; SMN2TP53
	SCHEMBL1784588	0.86	KDR (0.62)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1786745	0.86	HTT (0.42)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1786848	0.85	KDR (0.44)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1785373	0.85	KMT2A (0.47)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1788504	0.85	KDR (0.45)	KMT2AMEN1MAPTKDRLMNA
	SCHEMBL1787343	0.85	MAPK14 (0.43)	KDRSMN1; SMN2TP53KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.