SCHEMBL1786745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1787746	0.91	KDR (0.43)	HTTKMT2AMEN1MAPTKDR
	SCHEMBL1787390	0.89	GRM4 (0.41)	HTTKMT2AMEN1MAPTKDR
	SCHEMBL1788425	0.88	KDR (0.57)	HTTKMT2AMEN1MAPTKDR
	SCHEMBL1786545	0.87	KDR (0.45)	HTTKMT2AMEN1MAPTKDR
	SCHEMBL1785263	0.86	KMT2A (0.45)	HTTKMT2AMEN1MAPTKDR
	Hydrochloric Acid SCHEMBL1787604	0.83	ALDH1A1 (0.50)	MAPTKDRMAPK8LMNAL3MBTL1
	SCHEMBL1788117	0.83	MAPT (0.53)	HTTKMT2AMEN1MAPTKDR
	SCHEMBL1787441	0.83	KDR (0.42)	HTTKMT2AKDRLMNAHPGD
	SCHEMBL1783816	0.82	KDR (0.46)	HTTKMT2AMEN1MAPTKDR
	SCHEMBL1788504	0.81	KDR (0.45)	HTTKMT2AMEN1MAPTKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.