Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 4/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16441449 | 0.99 | PIK3CB (0.36) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16441512 | 0.94 | ALOX5 (0.35) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL17853043 | 0.94 | MAPT (0.35) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16431833 | 0.94 | TSHR (0.36) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16441403 | 0.92 | TSHR (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL17954746 | 0.90 | PIK3CB (0.37) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16441398 | 0.90 | KDM4E (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL17853046 | 0.90 | ALOX5 (0.35) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16441543 | 0.88 | ALOX5 (0.37) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL17703143 | 0.87 | ALOX5 (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210004-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | US | disclosed |
| US-20230210004-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | US | disclosed |
| US-11588117-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| EP-3647393-A1 | MATERIALS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | US | disclosed |
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPHB3, EPHA3, EPHB4 | PIK3CB 3402/4885PIK3CG 3208/4885PRKDC 1579/4885 |
| US-20230210004-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPHB3, EPHA3, EPHB4 | PIK3CB 3402/4885PIK3CG 3208/4885PRKDC 1579/4885 |
| US-11588117-B2 | Materials for electronic devices | EPHB3, EPHA3, EPHB4 | PIK3CB 3402/4885PIK3CG 3208/4885PRKDC 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.