Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 4/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.37 |
| ▸ | PRKDC | P78527 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431833 | 0.94 | TSHR (0.36) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16441449 | 0.91 | PIK3CB (0.36) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL22140592 | 0.90 | PRKDC (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16441543 | 0.90 | ALOX5 (0.37) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL17853042 | 0.90 | PIK3CB (0.36) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL17954751 | 0.90 | ABCG2 (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL16441398 | 0.89 | KDM4E (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL17703159 | 0.89 | ALOX5 (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL14295556 | 0.89 | ALOX5 (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL14295613 | 0.88 | ALOX5 (0.37) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016116520-A1 | PHENYLETHER-SUBSTITUTED ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |