Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17853042 | 0.94 | PIK3CB (0.36) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL17954746 | 0.94 | PIK3CB (0.37) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16441449 | 0.92 | PIK3CB (0.36) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16441543 | 0.91 | ALOX5 (0.37) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16441403 | 0.91 | TSHR (0.38) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL23154921 | 0.90 | MAPT (0.34) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL17853043 | 0.90 | MAPT (0.35) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL17703153 | 0.89 | ALOX5 (0.38) | TSHRKDM4EALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL17954751 | 0.88 | ABCG2 (0.38) | TSHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16441512 | 0.88 | ALOX5 (0.35) | TSHRMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179069-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2025-06-05 | — | — | US | disclosed |
| EP-3712229-A1 | MATERIALS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-3712229-A1 | MATERIALS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-3027708-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| EP-3027708-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| US-20160164002-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160164002-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160164002-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| EP-3027708-A1 | MATERIALS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015014435-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015014435-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179069-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPX, EFNA1, GPX4 | TSHR 4390/4885MAPT 3804/4885KDM4E 2527/4885 |
| US-20160164002-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPX, EFNA1, GPX4 | TSHR 4390/4885MAPT 3804/4885KDM4E 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.