Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17971011 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL17853277 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL18769029 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL17853275 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL18768950 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL17776318 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL10086608 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL22198371 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL22198424 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 | |
| SCHEMBL17776317 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922260-A2 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2021-12-15 | — | — | EP | disclosed |
| US-9902754-B2 | Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction | UNIVERSITY OF COPENHAGEN (DK) | 2018-02-27 | — | — | US | disclosed |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170107268-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-04-20 | — | — | US | disclosed |
| US-20160176924-A1 | MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION | UNIVERSITY OF COPENHAGEN (DK) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176924-A1 | MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION | PSD, GRIN1, GRIN3B | ALDH1A1 4849/4885LMNA 3985/4885SLC15A2 3311/4885 |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | ALDH1A1 4716/4885LMNA 4484/4885SLC15A2 2837/4885 |
| US-20170107268-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | ALDH1A1 4716/4885LMNA 4484/4885SLC15A2 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.