Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787544 | 0.92 | HTT (0.38) | TSHRTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL1785412 | 0.88 | — | — | |
| SCHEMBL1783369 | 0.82 | TSHR (0.43) | TSHRESR1CYP3A4ALDH1A1 | |
| SCHEMBL1784131 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL27600513 | 0.78 | — | — | |
| SCHEMBL3687070 | 0.78 | — | — | |
| SCHEMBL27619011 | 0.78 | — | — | |
| SCHEMBL3695203 | 0.78 | — | — | |
| SCHEMBL3692837 | 0.78 | — | — | |
| SCHEMBL19795474 | 0.76 | HSD17B10 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346334-B | Tetrafluorotoluene compound, method for producing same and use thereof | SUMITOMO CO LTD | 2013-04-24 | — | — | CN | disclosed |
| US-20120130118-A1 | METHODS FOR PRODUCING AND USING A TETRAFLUOROTOLUENE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20110124923-A1 | TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
| CN-101346334-A | Tetrafluorotoluene compound, method for producing same and use thereof | SUMITOMO CHEMICAL CO (JP) | 2009-01-14 | — | — | CN | disclosed |
| EP-1975147-A1 | TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130118-A1 | METHODS FOR PRODUCING AND USING A TETRAFLUOROTOLUENE COMPOUND | ADH1C, ADH1A, CYP2E1 | TSHR 839/4885TAS1R3 980/4885TAS1R1 639/4885 |
| US-20110124923-A1 | TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF | ADH1C, ADH1A, CYP2E1 | TSHR 842/4885TAS1R3 799/4885TAS1R1 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.