Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787296 | 0.93 | HTT (0.46) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL1785464 | 0.82 | TSHR (0.35) | TSHRESR1CYP3A4ALDH1A1 | |
| SCHEMBL1785703 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1787544 | 0.76 | HTT (0.38) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL1787702 | 0.71 | PTPN1 (0.33) | — | |
| SCHEMBL11579414 | 0.69 | MAOA (0.43) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL9511137 | 0.68 | LTA4H (0.46) | TSHRMEN1KMT2AMAPTESR1 | |
| SCHEMBL10985455 | 0.68 | GCGR (0.38) | — | |
| SCHEMBL509275 | 0.67 | TSHR (0.45) | TSHRMEN1KMT2AESR1LTA4H | |
| Alcohol SCHEMBL2397102 | 0.66 | TSHR (0.78) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130118-A1 | METHODS FOR PRODUCING AND USING A TETRAFLUOROTOLUENE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20110124923-A1 | TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-1975147-A1 | TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130118-A1 | METHODS FOR PRODUCING AND USING A TETRAFLUOROTOLUENE COMPOUND | ADH1C, ADH1A, CYP2E1 | TSHR 839/4885MEN1 621/4885THRB 1753/4885 |
| US-20110124923-A1 | TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF | ADH1C, ADH1A, CYP2E1 | TSHR 842/4885MEN1 636/4885THRB 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.