SCHEMBL17856602

SCHEMBL17856602

c1ccc2c(c1)oc1c(-c3nc4c(-c5cccc6c5oc5ccccc56)ccc(-c5cccc6c5oc5ccccc56)c4s3)cccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
PRKDC P78527 5/20 0.41
PIK3CD O00329 2/20 0.41
PIK3CB P42338 2/20 0.41
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
GGPS1 O95749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17856590 0.92 ALOX5 (0.46) ALOX5PRKDCPIK3CDPIK3CBMEN1
SCHEMBL17856626 0.90 PRKDC (0.43) ALOX5PRKDCPIK3CDPIK3CBMEN1
SCHEMBL17856616 0.89 PRKDC (0.44) ALOX5PRKDCPIK3CDPIK3CBMEN1
SCHEMBL17856668 0.88 ALOX5 (0.47) ALOX5PRKDCPIK3CDPIK3CBMEN1
SCHEMBL17856700 0.84 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBMEN1
SCHEMBL17856636 0.84 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBALDH1A1
SCHEMBL17856667 0.82 ALOX5 (0.42) ALOX5PRKDCPIK3CDPIK3CBMEN1
SCHEMBL17856657 0.82 ALOX5 (0.46) ALOX5PRKDCPIK3CDPIK3CBMEN1
SCHEMBL17856576 0.81 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL17856764 0.81 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9966538-B2 Compound, light-emitting element and electronic device comprising same LMS CO., LTD. (KR) 2018-05-08 US disclosed
US-9966538-B2 Compound, light-emitting element and electronic device comprising same LMS CO., LTD. (KR) 2018-05-08 US disclosed
US-20160181544-A1 Novel Compound, Light-Emitting Element and Electronic Device Comprising Same LMS CO., LTD. (KR) 2016-06-23 US disclosed
US-20160181544-A1 Novel Compound, Light-Emitting Element and Electronic Device Comprising Same LMS CO., LTD. (KR) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160181544-A1 Novel Compound, Light-Emitting Element and Electronic Device Comprising Same HSF1, CRY1, NFE2L2 ALOX5 1816/4885PRKDC 3566/4885PIK3CD 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.