SCHEMBL1785746

SCHEMBL1785746

CCC(C)(C)CCC(C)=O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.38
SLC15A2 Q16348 1/20 0.38
GAA P10253 1/20 0.36
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.32
PAOX Q6QHF9 1/20 0.32
FFAR1 O14842 1/20 0.31
CPT2 P23786 1/20 0.31
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782224 0.85 ALDH1A1 (0.41) ALDH1A1TDP1LMNASLC15A2GAA
SCHEMBL1781497 0.83 PAOX (0.43) ALDH1A1TDP1LMNASLC15A2GAA
SCHEMBL1783764 0.82 ALDH1A1 (0.43) ALDH1A1TDP1LMNASLC15A2GAA
SCHEMBL8897978 0.81 PAOX (0.46) ALDH1A1TDP1MEN1KMT2AACHE
SCHEMBL11564017 0.81 TDP1 (0.33) ALDH1A1TDP1MEN1CYP1A2THRB
SCHEMBL1572939 0.79 ALDH1A1 (0.52) ALDH1A1TDP1LMNAMEN1CYP1A2
SCHEMBL5705354 0.79 ALDH1A1 (0.32) ALDH1A1TDP1MEN1CYP1A2THRB
SCHEMBL10414762 0.79 ALDH1A1 (0.45) ALDH1A1TDP1LMNASLC15A2GAA
SCHEMBL20490036 0.79 ALDH1A1 (0.32) ALDH1A1TDP1MEN1CYP1A2THRB
SCHEMBL1783727 0.78 CES1 (0.39) ALDH1A1TDP1MEN1KMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562921-B1 LUBRICATING COMPOSITION INCLUDING N-ALKYLATED DIANILINE LUBRIZOL CORP (US) 2022-04-27 EP disclosed
CN-110114448-B Lubricating composition with alkylated naphthylamines 路博润公司 2022-03-04 CN disclosed
US-11162048-B2 Lubricating composition with alkylated naphthylamine THE LUBRIZOL CORPORATION (US) 2021-11-02 US disclosed
EP-3562922-B1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE LUBRIZOL CORP (US) 2021-02-03 EP disclosed
EP-3562922-A1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE The Lubrizol Corporation (US) 2019-11-06 EP disclosed
EP-3562921-A1 LUBRICATING COMPOSITION INCLUDING N-ALKYLATED DIANILINE The Lubrizol Corporation (US) 2019-11-06 EP disclosed
US-20190316056-A1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE THE LUBRIZOL CORPORATION (US) 2019-10-17 US disclosed
WO-2018125569-A1 LUBRICATING COMPOSITION INCLUDING N-ALKYLATED DIANILINE THE LUBRIZOL CORPORATION (US) 2018-07-05 WO disclosed
WO-2018125567-A1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE THE LUBRIZOL CORPORATION (US) 2018-07-05 WO disclosed
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed
US-7186782-B2 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2007-03-06 US disclosed
US-20060041079-A1 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION 2006-02-23 US disclosed
US-6881797-B2 Process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2005-04-19 US disclosed
US-20040082727-A1 Process for hydrogenation of conjugated diene polymer TSRC CORPORATION (CN) 2004-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 ALDH1A1 520/4885TDP1 3995/4885LMNA 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.