SCHEMBL17857795

SCHEMBL17857795

NNC(=O)N(OC(F)(F)F)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
PDK1 Q15118 3/20 0.33
PDK2 Q15119 3/20 0.33
PDK3 Q15120 3/20 0.33
PDK4 Q16654 3/20 0.33
CTSD P07339 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CES1 P23141 1/20 0.32
ALDH1A1 P00352 4/20 0.32
KDM4E B2RXH2 2/20 0.32
TACR1 P25103 1/20 0.32
MLYCD O95822 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27617832 0.82 PDK1 (0.38) NPSR1PDK1PDK2PDK3PDK4
SCHEMBL6012131 0.81 NPSR1 (0.38) NPSR1ATMTDP1L3MBTL1CES1
SCHEMBL5170181 0.80 NPSR1 (0.40) NPSR1ATMTDP1L3MBTL1CES1
SCHEMBL17681708 0.78 ALDH1A1 (0.41) NPSR1PDK1PDK2PDK3PDK4
SCHEMBL17681664 0.77 KMT2A (0.38) NPSR1PDK1PDK2PDK3PDK4
SCHEMBL8084617 0.77 CES1 (0.39) NPSR1ATMTDP1L3MBTL1CES1
SCHEMBL9505610 0.77 NPSR1 (0.40) NPSR1CTSDL3MBTL1CES1ALDH1A1
SCHEMBL29556411 0.74 SMN1; SMN2 (0.37) NPSR1PDK1PDK2PDK3PDK4
SCHEMBL31150210 0.74 ALDH1A1 (0.48) L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL7149426 0.73 AKT1 (0.36) NPSR1ATMTDP1L3MBTL1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113030292-A Method for analyzing content of p-trifluoromethoxyaniline formylhydrazine 京博农化科技有限公司 2021-06-25 CN claimed
US-9375001-B1 Granular fly bait WELLMARK INTERNATIONAL (US) 2016-06-28 US disclosed