Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2503173 | 0.90 | — | — | |
| SCHEMBL21402318 | 0.86 | TBXAS1 (0.48) | ALDH1A1KDM4ELMNATBXAS1CYP11B1 | |
| SCHEMBL12223690 | 0.85 | TBXAS1 (0.45) | ALDH1A1KDM4ELMNATBXAS1MAPK1 | |
| SCHEMBL21402319 | 0.83 | TBXAS1 (0.55) | ALDH1A1KDM4ELMNATBXAS1KMT2A | |
| SCHEMBL5148219 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNATBXAS1NPSR1 | |
| SCHEMBL285083 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNATBXAS1NPSR1 | |
| SCHEMBL2650266 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNATBXAS1MAPK1 | |
| Sulfuric Acid SCHEMBL28167966 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNATBXAS1 | |
| SCHEMBL8387191 | 0.79 | TBXAS1 (0.59) | ALDH1A1KDM4ELMNATBXAS1NPSR1 | |
| SCHEMBL1344806 | 0.79 | TBXAS1 (0.39) | ALDH1A1KDM4ELMNATBXAS1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100716-A1 | REVERSIRTM COMPOUNDS | JADHAV VASANT (US) | 2016-06-23 | — | — | WO | disclosed |