SCHEMBL8387191

SCHEMBL8387191

CCOCCCn1ccnc1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 3/20 0.59
KDM4E B2RXH2 2/20 0.58
LMNA P02545 1/20 0.58
QPCT Q16769 1/20 0.55
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
ATM Q13315 1/20 0.54
ALDH1A1 P00352 4/20 0.53
NPSR1 Q6W5P4 1/20 0.52
TP53 P04637 1/20 0.51
GAA P10253 1/20 0.51
MAPK1 P28482 1/20 0.51
HSD17B10 Q99714 1/20 0.51
HTT P42858 1/20 0.51
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8386533 0.95 LMNA (0.65) TBXAS1KDM4ELMNAMEN1KMT2A
SCHEMBL22268749 0.93 TBXAS1 (0.66) TBXAS1KDM4ELMNAMEN1KMT2A
SCHEMBL285083 0.89 ALDH1A1 (0.62) TBXAS1KDM4ELMNAMEN1KMT2A
SCHEMBL5148219 0.85 ALDH1A1 (0.68) TBXAS1KDM4ELMNAMEN1KMT2A
SCHEMBL27342892 0.85 KDM4E (0.48) TBXAS1KDM4ELMNAQPCTMEN1
SCHEMBL31616982 0.84 QPCT (0.50) TBXAS1KDM4ELMNAQPCTKMT2A
SCHEMBL762532 0.81 TBXAS1 (0.63) TBXAS1KDM4ELMNAQPCTMEN1
SCHEMBL24160933 0.81 KMT2A (0.55) TBXAS1KDM4ELMNAQPCTMEN1
SCHEMBL18512362 0.81 TBXAS1 (0.69) TBXAS1KDM4ELMNAMEN1KMT2A
SCHEMBL18511817 0.81 TBXAS1 (0.74) TBXAS1KDM4ELMNAQPCTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3546443-B1 METHOD FOR PRODUCING FLUORINE-CONTAINING DIALKYL CARBONATE COMPOUNDS SAMHWA PAINTS IND CO LTD (KR) 2021-11-17 EP claimed
US-10889537-B2 Method for producing fluorine-containing dialkyl carbonate compounds SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2021-01-12 US claimed
US-20200231530-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING DIALKYL CARBONATE COMPOUNDS SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2020-07-23 US claimed
EP-3546443-A2 METHOD FOR PRODUCING FLUORINE-CONTAINING DIALKYL CARBONATE COMPOUNDS Samhwa Paints Industries Co., Ltd. (KR) 2019-10-02 EP claimed
EP-3587388-B1 METHOD FOR PREPARING FLUORINATED METHACRYLATE COMPOUND SAMHWA PAINTS IND CO LTD (KR) 2023-08-16 EP disclosed
EP-3546443-B1 METHOD FOR PRODUCING FLUORINE-CONTAINING DIALKYL CARBONATE COMPOUNDS SAMHWA PAINTS IND CO LTD (KR) 2021-11-17 EP disclosed
US-10889537-B2 Method for producing fluorine-containing dialkyl carbonate compounds SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2021-01-12 US disclosed
US-10752574-B2 Method for preparing fluorinated methacrylate compound SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2020-08-25 US disclosed
US-20200231530-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING DIALKYL CARBONATE COMPOUNDS SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2020-07-23 US disclosed
EP-3546443-A2 METHOD FOR PRODUCING FLUORINE-CONTAINING DIALKYL CARBONATE COMPOUNDS Samhwa Paints Industries Co., Ltd. (KR) 2019-10-02 EP disclosed
EP-3507346-A1 ALKYLATION OF REFINERY PENTENES WITH ISOBUTANE Chevron U.S.A. Inc. (US) 2019-07-10 EP disclosed
WO-2018044406-A1 ALKYLATION OF REFINERY PENTENES WITH ISOBUTANE CHEVRON U.S.A. INC. (US) 2018-03-08 WO disclosed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP disclosed
EP-0597411-B1 Process for the preparation of phthalocyanine reactive dyes BASF AG (DE) 1999-04-28 EP disclosed
US-5516901-A Preparation of reactive phthalocyanine dyes BASF AKTIENGESELLSCHAFT (DE) 1996-05-14 US disclosed
US-5444163-A Preparation of reactive phthalocyanine dyes BASF AKTIENGESELLSCHAFT (DE) 1995-08-22 US disclosed
EP-0602562-A1 Process for the preparation of phthalocyanine reactive dyes BASF Aktiengesellschaft (DE) 1994-06-22 EP disclosed
EP-0597411-A1 Process for the preparation of phthalocyanine reactive dyes BASF Aktiengesellschaft (DE) 1994-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10889537-B2 Method for producing fluorine-containing dialkyl carbonate compounds CA3, CDA, CHKB TBXAS1 2714/4885KDM4E 650/4885LMNA 2448/4885
US-20200231530-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING DIALKYL CARBONATE COMPOUNDS CA3, GK, CLK3 TBXAS1 3199/4885KDM4E 2108/4885LMNA 2156/4885
US-10752574-B2 Method for preparing fluorinated methacrylate compound MMAB, ALKBH5, MEP1A TBXAS1 1254/4885KDM4E 271/4885LMNA 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.