SCHEMBL17859400

SCHEMBL17859400

C[Si](C)(C)c1cc2cc3c(cc2cc1[Si](C)(C)C)C(=O)c1cc2cc([Si](C)(C)C)c([Si](C)(C)C)cc2cc1C3=O

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ESR1 P03372 1/20 0.31
MAOA P21397 1/20 0.31
UGT1A1 P22309 1/20 0.31
MAOB P27338 1/20 0.31
ESR2 Q92731 1/20 0.31
USP8 P40818 1/20 0.31
USP7 Q93009 1/20 0.31
ATM Q13315 1/20 0.31
BCL2 P10415 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586058 0.81 IDO1 (0.30)
SCHEMBL4586844 0.78
SCHEMBL4867772 0.78
SCHEMBL12403126 0.71
SCHEMBL452078 0.70 ELANE (0.41) ELANENPC1RAB9AESR1MAOA
SCHEMBL9804870 0.68 ELANE (0.44) ELANENPC1RAB9AMAOBUSP8
SCHEMBL4572706 0.67 IDO1 (0.32)
SCHEMBL5010157 0.65 LMNA (0.46)
SCHEMBL650112 0.65 MAOB (0.35) ELANENPC1RAB9AESR1MAOA
SCHEMBL1952272 0.65 S100A4 (0.40) ELANEESR1MAOAUGT1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016100754-A1 QUANTITATIVE INTRAMOLECULAR FISSION IN OLIGOACENES, MATERIALS, AND METHODS OF USE THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-06-23 WO disclosed