Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 10/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609650 | 0.78 | NPC1 (0.38) | TYMSARMEN1KMT2AATM | |
| SCHEMBL1188564 | 0.77 | TYMS (0.41) | TYMSALOX15TDP1MEN1ALDH1A1 | |
| SCHEMBL27085505 | 0.75 | TYMS (0.51) | TYMSARALOX15TDP1KDM4E | |
| SCHEMBL24166827 | 0.75 | TYMS (0.42) | TYMSCYP1A2ALOX15TDP1MEN1 | |
| SCHEMBL19239490 | 0.74 | MEN1 (0.40) | ARALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL12296041 | 0.74 | TYMS (0.41) | TYMSALOX15TDP1MEN1ALDH1A1 | |
| SCHEMBL29580210 | 0.74 | TYMS (0.41) | TYMSALOX15TDP1MEN1ALDH1A1 | |
| SCHEMBL4324585 | 0.74 | TYMS (0.41) | TYMSALOX15TDP1MEN1ALDH1A1 | |
| SCHEMBL2607526 | 0.74 | TYMS (0.41) | TYMSARALOX15TDP1MEN1 | |
| SCHEMBL32670397 | 0.74 | TYMS (0.41) | TYMSALOX15TDP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175292-A1 | Antioxidants Having Aromatic Structures Reacting with Superoxide | TOUR JAMES (US) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175292-A1 | Antioxidants Having Aromatic Structures Reacting with Superoxide | GPX4, TXN2, MPO | TYMS 1370/4885AR 2174/4885CYP1A1 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.