Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882032 | 0.88 | PRKCA (0.45) | PRKCAPRKCDCA2CA1HDAC1 | |
| SCHEMBL17860729 | 0.88 | CA2 (0.35) | CA2CA1MAPK1TSHRCTSK | |
| SCHEMBL17860703 | 0.81 | PRKCA (0.41) | PRKCAPRKCDCA2CA1HDAC1 | |
| SCHEMBL12790573 | 0.80 | CA2 (0.48) | PRKCAPRKCDCA2CA1HDAC1 | |
| SCHEMBL17878560 | 0.80 | PRKCA (0.40) | PRKCAPRKCDCA2CA1HDAC1 | |
| SCHEMBL9076903 | 0.79 | PRKCA (0.39) | PRKCAPRKCDCA2CA1HDAC1 | |
| SCHEMBL4106619 | 0.76 | PRKCA (0.45) | PRKCAPRKCDCA2CA1HDAC1 | |
| SCHEMBL17860697 | 0.75 | CA2 (0.40) | PRKCAPRKCDCA2CA1MAPK1 | |
| SCHEMBL25275003 | 0.75 | PRKCA (0.44) | PRKCAPRKCDCA2CA1HDAC1 | |
| SCHEMBL17882022 | 0.75 | PRKCA (0.44) | PRKCAPRKCDCA2CA1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |