Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860690 | 0.88 | PRKCA (0.41) | CA2CA1TSHRCTSKMAPK1 | |
| SCHEMBL17860697 | 0.86 | CA2 (0.40) | CA2CA1USP2TSHRCTSK | |
| SCHEMBL12790573 | 0.78 | CA2 (0.48) | CA2CA1TSHRCTSKMAPK1 | |
| SCHEMBL17878558 | 0.77 | BIRC2 (0.37) | CA2CA1USP2TSHRCTSK | |
| SCHEMBL1534782 | 0.74 | ALDH1A1 (0.37) | CA2CA1USP2TSHRMAPK1 | |
| SCHEMBL17882032 | 0.74 | PRKCA (0.45) | CA2CA1USP2TSHRCTSK | |
| SCHEMBL304879 | 0.73 | ALDH1A1 (0.36) | CTSKALDH1A1 | |
| SCHEMBL827371 | 0.72 | CTSK (0.35) | CA2CA1TSHRCTSKALDH1A1 | |
| SCHEMBL17860707 | 0.71 | ALDH1A1 (0.48) | CA2CA1TSHRMAPK1ALDH1A1 | |
| SCHEMBL4834711 | 0.70 | TSHR (0.36) | TSHRCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |