Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2134773 | 0.79 | KDM1A (0.61) | KDM1AMAOBIDO1MAP4K4KMO | |
| SCHEMBL31689000 | 0.79 | KDM1A (0.54) | KDM1AMAOBIDO1MAP4K4KMO | |
| SCHEMBL10264655 | 0.79 | CYP3A4 (0.54) | KDM1AMAOBIDO1MAP4K4KMO | |
| SCHEMBL6863681 | 0.79 | HPGDS (0.56) | IDO1MAP4K4KMOFYNHSD17B1 | |
| SCHEMBL19992669 | 0.77 | KDM1A (0.49) | KDM1AMAOBKMOFYNNOTUM | |
| SCHEMBL15097694 | 0.77 | LDHA (0.52) | — | |
| SCHEMBL2609359 | 0.75 | MAOB (0.50) | KDM1AMAOBIDO1MAP4K4KMO | |
| SCHEMBL19992829 | 0.75 | KDM1A (0.57) | KDM1AMAOBIDO1KMOSCN2A | |
| SCHEMBL17882026 | 0.75 | MAOB (0.50) | KDM1AMAOBIDO1FYNDHFR | |
| SCHEMBL11683554 | 0.74 | KDM1A (0.53) | KDM1AMAOBIDO1MAP4K4KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |