Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17863953 | 1.00 | MAPT (0.41) | MAPTMAPK1HIF1AALDH1A1TDP1 | |
| SCHEMBL25398613 | 0.81 | MAPT (0.41) | MAPTMAPK1HIF1AALDH1A1TDP1 | |
| SCHEMBL14853753 | 0.81 | ABCB1 (0.45) | MAPTMAPK1HIF1AALDH1A1ABCB1 | |
| SCHEMBL17860798 | 0.79 | POLB (0.42) | MAPTTDP1KMT2AMEN1USP2 | |
| SCHEMBL17861870 | 0.79 | HTR3E (0.37) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL17863951 | 0.78 | MAPT (0.35) | MAPTABCB1 | |
| SCHEMBL20227072 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ABCB1 | |
| SCHEMBL4283223 | 0.77 | ABCB1 (0.44) | MAPTALDH1A1ABCB1 | |
| SCHEMBL4283219 | 0.77 | ABCB1 (0.44) | MAPTALDH1A1ABCB1 | |
| SCHEMBL3975101 | 0.77 | ABCB1 (0.42) | MAPTABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100569-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2016-06-23 | — | — | WO | disclosed |