Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20227073 | 0.81 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL26290154 | 0.81 | ABCB1 (0.46) | ABCB1BCHE | |
| SCHEMBL26277654 | 0.79 | ABCB1 (0.39) | ALDH1A1ABCB1BCHE | |
| SCHEMBL7149873 | 0.78 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL11398254 | 0.78 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL17860797 | 0.78 | MAPT (0.41) | ALDH1A1ABCB1 | |
| SCHEMBL17863953 | 0.78 | MAPT (0.41) | ALDH1A1ABCB1 | |
| SCHEMBL5492148 | 0.75 | MAPT (0.48) | ABCB1BCHE | |
| SCHEMBL7152559 | 0.75 | ABCB1 (0.43) | ALDH1A1ABCB1BCHE | |
| SCHEMBL5492143 | 0.75 | MAPT (0.48) | ABCB1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155384-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155384-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NT5C3B, NT5C2 | ALDH1A1 2737/4885ABCB1 1275/4885BCHE 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.