Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645760 | 0.88 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL17848826 | 0.85 | FFAR3 (0.41) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL17882018 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL5837034 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9847820 | 0.79 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL24106170 | 0.79 | CES1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL18290180 | 0.78 | STING1 (0.36) | — | |
| SCHEMBL17860695 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28406124 | 0.77 | DGKA (0.48) | ALDH1A1LMNA | |
| SCHEMBL4935949 | 0.76 | LMNA (0.35) | ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |