SCHEMBL17862158

SCHEMBL17862158

CCCCCc1ccc(-c2ccc(OC(F)(F)c3cc(F)c(F)c(F)c3)cc2)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.34
RORC P51449 3/20 0.34
RORA P35398 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
CNR2 P34972 3/20 0.33
TSHR P16473 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPT P10636 1/20 0.32
TYR P14679 1/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
S1PR1 P21453 3/20 0.31
GCGR P47871 1/20 0.31
PPARA Q07869 1/20 0.31
S1PR3 Q99500 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17368028 0.92 CTSL (0.36) RORC
SCHEMBL17367978 0.91 RARB (0.34) RARBRORCRORANR1H4CNR2
SCHEMBL17367992 0.88 CTSL (0.34) RORCRORANR1H4S1PR1S1PR3
SCHEMBL17365895 0.87 RORC (0.33) RARBRORCRORANR1H4CNR2
SCHEMBL17368008 0.84 APP (0.34) RORCRORANR1H4S1PR1S1PR3
SCHEMBL9060800 0.84 HDAC3 (0.38) RARBCNR2TSHRMEN1TP53
SCHEMBL17365786 0.84 CTSL (0.34) PPARACNR1
SCHEMBL17368018 0.84 CTSL (0.34) PPARACNR1
SCHEMBL9060439 0.83 HDAC3 (0.37) CNR2PPARA
SCHEMBL17368015 0.83 VDR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160177180-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-06-23 US disclosed