SCHEMBL1786466

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1788104	0.90	KDR (0.47)	KDRNPC1KMT2AKDM4EMEN1
	SCHEMBL1786820	0.87	KDR (0.46)	KDRNPC1TSHRKMT2AMEN1
	SCHEMBL1787441	0.86	KDR (0.42)	KDRKMT2AKDM4EALDH1A1LMNA
	SCHEMBL1785328	0.86	MAPT (0.50)	KDRNPC1KMT2ASMN1; SMN2MAPT
	SCHEMBL1784588	0.86	KDR (0.62)	KDRNPC1TSHRKMT2AKDM4E
	SCHEMBL1788178	0.83	MEN1 (0.51)	KMT2AKDM4EMEN1ALDH1A1LMNA
	SCHEMBL1786239	0.83	KDR (0.40)	KDRNPC1KMT2AKDM4EALDH1A1
	SCHEMBL1787465	0.83	KDR (0.39)	KDRNPC1KMT2AMEN1ALDH1A1
	SCHEMBL1786747	0.82	KDR (0.66)	KDRNPC1TSHRKMT2AKDM4E
	SCHEMBL1788425	0.82	KDR (0.57)	KDRNPC1TSHRKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.