SCHEMBL1786239

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1787441	0.97	KDR (0.42)	KDRHSD11B1LMNAKMT2AKDM4E
	SCHEMBL1786545	0.85	KDR (0.45)	KDRLMNAKMT2AKDM4ENPC1
	SCHEMBL1785263	0.84	KMT2A (0.45)	KDRLMNAKMT2AKDM4ENPC1
	SCHEMBL1786466	0.83	KDR (0.59)	KDRHSD11B1LMNAKMT2AKDM4E
	SCHEMBL1788104	0.83	KDR (0.47)	KDRLMNAKMT2AKDM4ENPC1
	SCHEMBL1787746	0.81	KDR (0.43)	KDRLMNAKMT2AKDM4ENPC1
	SCHEMBL1788178	0.81	MEN1 (0.51)	LMNAKMT2AKDM4EHTTTP53
	SCHEMBL1786745	0.80	HTT (0.42)	KDRHSD11B1MAPK8LMNAKMT2A
	SCHEMBL1783816	0.80	KDR (0.46)	KDRLMNAKMT2AKDM4ENPC1
	SCHEMBL1940635	0.80	KDR (0.49)	KDRHSD11B1LMNAKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.