Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19729056 | 0.83 | GABRA1 (0.41) | — | |
| SCHEMBL17865232 | 0.75 | HTR2B (0.41) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL13385205 | 0.73 | RAPGEF4 (0.35) | LMNAHTR2B | |
| SCHEMBL17865231 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL17865246 | 0.67 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL20636510 | 0.66 | LMNA (0.42) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL16413144 | 0.66 | TSHR (0.44) | CHRM1 | |
| SCHEMBL25857321 | 0.66 | TSHR (0.44) | CHRM1 | |
| SCHEMBL27102760 | 0.65 | KDM4E (0.32) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL19729052 | 0.65 | EIF4A3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360760-A1 | Inhibitors of Bromodomains | ZENITH EPIGENETICS CORP. (CA) | 2017-12-21 | — | — | US | disclosed |
| WO-2016097863-A1 | INHIBITORS OF BROMODOMAINS | ZENITH EPIGENETICS CORP. (CA) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360760-A1 | Inhibitors of Bromodomains | BRDT, BRD3, BRPF3 | TRPA1 4872/4885LMNA 2745/4885CHRM1 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.