Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865731 | 0.83 | L3MBTL1 (0.50) | L3MBTL1HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL17969615 | 0.83 | L3MBTL1 (0.50) | L3MBTL1HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL20153491 | 0.83 | L3MBTL1 (0.50) | L3MBTL1HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL19521198 | 0.78 | HTT (0.35) | L3MBTL1TSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17865741 | 0.75 | DDB1 (0.42) | L3MBTL1ALDH1A1KDM4EMAPK1MAPT | |
| SCHEMBL17865749 | 0.75 | DDB1 (0.42) | L3MBTL1ALDH1A1KDM4EMAPK1MAPT | |
| SCHEMBL19521177 | 0.74 | ADAMTS5 (0.48) | — | |
| SCHEMBL8325259 | 0.73 | L3MBTL1 (0.68) | L3MBTL1HSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL19521183 | 0.72 | CCR1 (0.41) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL21852720 | 0.71 | L3MBTL1 (0.64) | L3MBTL1HSD17B10ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036219-A2 | NOVEL BETA LACTAMS AS MODULATORS OF GLUTAMATE UPTAKE AND METHODS FOR USE THEREOF | Temple University Of The Commonwealth System Of Higher Education (US) | 2016-06-29 | — | — | EP | disclosed |