Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192426 | 0.85 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL192337 | 0.83 | CA2 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL192440 | 0.83 | CA2 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL17865951 | 0.81 | PRMT5 (0.38) | PRMT5WDR77METTL3 | |
| SCHEMBL17866033 | 0.78 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL17865964 | 0.74 | SLC29A1 (0.51) | — | |
| SCHEMBL10004854 | 0.70 | NAE1 (0.52) | — | |
| SCHEMBL17865978 | 0.70 | NAE1 (0.46) | PRMT5WDR77METTL3 | |
| SCHEMBL191544 | 0.70 | SLC29A1 (0.39) | PRMT5WDR77 | |
| SCHEMBL17865955 | 0.70 | NAE1 (0.51) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402334-B1 | Inhibitors of E1 Activating Enzymes | MILLENNIUM PHARM INC (US) | 2016-06-29 | — | — | EP | claimed |