Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.49 |
| ▸ | CDK2 | P24941 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CCNH | P51946 | 1/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865958 | 0.87 | TP53 (0.45) | — | |
| SCHEMBL10005049 | 0.84 | ADORA3 (0.52) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL18872506 | 0.84 | ADORA3 (0.52) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL17865968 | 0.84 | ADORA3 (0.49) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL10005047 | 0.82 | ADORA3 (0.52) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL192286 | 0.81 | NAE1 (0.54) | ADORA3ADORA2AADORA1 | |
| SCHEMBL17865921 | 0.79 | METTL3 (0.54) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL17865956 | 0.79 | NAE1 (0.43) | — | |
| SCHEMBL17865976 | 0.78 | CCNA2 (0.44) | CCNA2CDK2CDK5CDK5R1ADORA3 | |
| SCHEMBL17865979 | 0.76 | METTL3 (0.40) | CCNA2CDK2CDK5CDK5R1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402334-B1 | Inhibitors of E1 Activating Enzymes | MILLENNIUM PHARM INC (US) | 2016-06-29 | — | — | EP | claimed |