SCHEMBL17866547

SCHEMBL17866547

N#Cc1ccc(-c2ccccn2)c(C#N)c1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 3/20 0.43
GRM5 P41594 3/20 0.41
KDM4E B2RXH2 3/20 0.39
POLB P06746 2/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
METAP1 P53582 1/20 0.39
BLM P54132 1/20 0.39
HIF1A Q16665 1/20 0.39
DOHH Q9BU89 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
ALDH1A1 P00352 3/20 0.39
GAA P10253 3/20 0.39
HPGD P15428 3/20 0.39
GLA P06280 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920234 0.82 KDM4E (0.43) SQORGRM5KDM4EPOLBLMNA
SCHEMBL30814370 0.81 GRIA1 (0.43) SQORGRM5KDM4EPOLBLMNA
SCHEMBL28856972 0.81 GRIA1 (0.43) SQORGRM5KDM4EPOLBLMNA
SCHEMBL31660805 0.80 SQOR (0.45) SQORGRM5KDM4EPOLBLMNA
SCHEMBL30150883 0.79 SQOR (0.44) SQORGRM5KDM4EPOLBLMNA
SCHEMBL3048746 0.79 SQOR (0.44) SQORGRM5KDM4EPOLBLMNA
SCHEMBL18411239 0.79 GRIA1 (0.44) SQORGRM5KDM4EPOLBLMNA
SCHEMBL22315755 0.79 EGLN2 (0.48) SQORGRM5KDM4EPOLBLMNA
SCHEMBL12679741 0.78 KDM4E (0.50) SQORGRM5KDM4EPOLBLMNA
SCHEMBL31660664 0.78 SQOR (0.46) SQORGRM5KDM4EPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10121976-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-11-06 US disclosed
US-20160190483-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10121976-B2 Organometallic compound and organic light-emitting device including the same TLL1, TBL2, TBL3 SQOR 2744/4885GRM5 2156/4885KDM4E 4004/4885
US-20160190483-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TLL1, TBL2, TBL3 SQOR 2744/4885GRM5 2156/4885KDM4E 4004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.