SCHEMBL3048746

SCHEMBL3048746

N#Cc1c(F)ccc(-c2ccccn2)c1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 3/20 0.44
GRM5 P41594 7/20 0.42
KDM4E B2RXH2 6/20 0.41
LMNA P02545 3/20 0.41
POLB P06746 2/20 0.41
CCR1 P32246 2/20 0.41
CCR5 P51681 2/20 0.41
CCR8 P51685 2/20 0.41
CYP1A2 P05177 1/20 0.41
METAP1 P53582 1/20 0.41
BLM P54132 1/20 0.41
HIF1A Q16665 1/20 0.41
DOHH Q9BU89 1/20 0.41
P4HTM Q9NXG6 1/20 0.41
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
GLA P06280 2/20 0.39
GAA P10253 2/20 0.39
HCRTR1 O43613 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30150883 1.00 SQOR (0.44) SQORGRM5KDM4ELMNAPOLB
2-Picolinic Acid SCHEMBL5927804 0.85 GRM4 (0.42) SQORGRM5KDM4ELMNAP4HTM
SCHEMBL16681034 0.82 SQOR (0.45) SQORGRM5KDM4ELMNAPOLB
SCHEMBL19258863 0.82 SQOR (0.41) SQORGRM5KDM4ELMNAPOLB
SCHEMBL27988588 0.81 CLK4 (0.36) SQORGRM5KDM4ECYP1A2ALDH1A1
SCHEMBL31660877 0.81 SQOR (0.51) SQORGRM5KDM4EPOLBALDH1A1
SCHEMBL17866547 0.79 SQOR (0.43) SQORGRM5KDM4ELMNAPOLB
SCHEMBL19258820 0.79 TGFBR1 (0.37) SQORGRM5KDM4EALDH1A1HPGD
SCHEMBL29901541 0.79 KDM4E (0.50) GRM5KDM4ELMNAPOLBCCR1
SCHEMBL1356335 0.79 KDM4E (0.50) GRM5KDM4ELMNAPOLBCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795190-B Organic iridium complex for organic electroluminescent element 田中贵金属工业株式会社 2020-02-21 CN disclosed
US-20190157574-A1 Phosphorescence Device Containing Heterocyclic Phosphate Metal Complexes AAC Technologies Pte. Ltd. (SG) 2019-05-23 US disclosed
US-10256418-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-04-09 US disclosed
EP-3187503-B1 ORGANOIRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENT TANAKA PRECIOUS METAL IND (JP) 2019-03-27 EP disclosed
EP-3187503-B1 ORGANOIRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENT TANAKA PRECIOUS METAL IND (JP) 2019-03-27 EP disclosed
US-9859511-B2 Organoiridium complex for organic electroluminescent elements TANAKA KIKINZOKU KOGYO K.K. (JP) 2018-01-02 US disclosed
US-20170237021-A1 ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS TANAKA KIKINZOKU KOGYO K.K. (JP) 2017-08-17 US disclosed
US-20170237021-A1 ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS TANAKA KIKINZOKU KOGYO K.K. (JP) 2017-08-17 US disclosed
EP-3187503-A1 ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS Tanaka Kikinzoku Kogyo K.K. (JP) 2017-07-05 EP disclosed
EP-3187503-A1 ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS Tanaka Kikinzoku Kogyo K.K. (JP) 2017-07-05 EP disclosed
US-20160028024-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2016-01-28 US disclosed
US-20150333278-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD., (KR) 2015-11-19 US disclosed
US-7915414-B2 Blue-emitting organometallic complexes and their application Chi, Yun (TW) 2011-03-29 US disclosed
US-7776458-B2 Used for forming an organic layer of the organic electroluminescent device, can emit light in the wavelength range of 400-650 nm, and induce white electroluminescence when combined with green or red luminescent materials; heat resistance; highly efficient Used for forming phospholuminescence; OLEDs SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-17 US disclosed
US-7776458-B2 Used for forming an organic layer of the organic electroluminescent device, can emit light in the wavelength range of 400-650 nm, and induce white electroluminescence when combined with green or red luminescent materials; heat resistance; highly efficient Used for forming phospholuminescence; OLEDs SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-17 US disclosed
US-7678473-B2 Organometallic complex and organic electroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-03-16 US disclosed
US-7541100-B2 Organic metal compounds in which compounds for host and compounds for dopant are connected, organic electroluminesence display devices using the compounds and method for preparation of the devices SAMSUNG DISPLAY CO., LTD. (KR) 2009-06-02 US disclosed
US-7541100-B2 Organic metal compounds in which compounds for host and compounds for dopant are connected, organic electroluminesence display devices using the compounds and method for preparation of the devices SAMSUNG DISPLAY CO., LTD. (KR) 2009-06-02 US disclosed
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application Chi, Yun (TW) 2008-05-29 US disclosed
US-20060228582-A1 Used for forming an organic layer of the organic electroluminescent device, can emit light in the wavelength range of 400-650 nm, and induce white electroluminescence when combined with green or red luminescent materials; heat resistance; highly efficient Used for forming phospholuminescence; OLEDs SAMSUNG DISPLAY CO., LTD. (KR) 2006-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10256418-B2 Organometallic compound and organic light-emitting device including the same L1CAM, AP1M1, NOM1 SQOR 1532/4885GRM5 3067/4885KDM4E 3683/4885
US-20170237021-A1 ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS L1CAM, ETFA, TTI2 SQOR 877/4885GRM5 3368/4885KDM4E 2850/4885
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application CYBA, IK, CRY1 SQOR 50/4885GRM5 2471/4885KDM4E 1230/4885
US-20160028024-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CHRM1, L1CAM, CHRM2 SQOR 1441/4885GRM5 3793/4885KDM4E 4287/4885
US-20190157574-A1 Phosphorescence Device Containing Heterocyclic Phosphate Metal Complexes TRPC1, TRPC4, TRPC7 SQOR 3017/4885GRM5 3038/4885KDM4E 4253/4885
US-20150333278-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, AP1M1, NOM1 SQOR 1532/4885GRM5 3067/4885KDM4E 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.