SCHEMBL17866722

SCHEMBL17866722

CC(C)CCc1c(C(=O)O)c(O)cc2c1C(=O)c1c(O)cc(O)cc1C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JUN P05412 1/20 0.56
SLC37A4 O43826 2/20 0.54
MEN1 O00255 2/20 0.50
ALDH1A1 P00352 2/20 0.50
POLB P06746 2/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
APEX1 P27695 2/20 0.50
MAPK1 P28482 2/20 0.50
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50
RECQL P46063 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
EGFR P00533 2/20 0.48
CDK4 P11802 2/20 0.48
CCND1 P24385 2/20 0.48
ELANE P08246 2/20 0.46
HSD17B10 Q99714 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16431129 0.84 SLC37A4 (0.74) JUNSLC37A4MEN1ALDH1A1POLB
SCHEMBL3277618 0.78 ELANE (0.54) MEN1ALDH1A1POLBCYP3A4MAPT
SCHEMBL29356605 0.76 CYP3A4 (0.60) JUNSLC37A4MEN1ALDH1A1POLB
SCHEMBL2138871 0.76 CYP3A4 (0.60) JUNSLC37A4MEN1ALDH1A1POLB
Anthraquinone SCHEMBL3670422 0.72 JUN (0.95) JUNSLC37A4MEN1ALDH1A1POLB
SCHEMBL16431884 0.72 JUN (1.00) JUNSLC37A4MEN1ALDH1A1POLB
SCHEMBL29390162 0.70 ESR1 (0.77) MEN1ALDH1A1POLBCYP3A4MAPT
SCHEMBL5968219 0.70 ESR1 (0.77) MEN1ALDH1A1POLBCYP3A4MAPT
SCHEMBL23199115 0.70 ELANE (0.62) MEN1ALDH1A1POLBCYP3A4MAPT
SCHEMBL29359585 0.70 ELANE (0.62) MEN1ALDH1A1POLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed