Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277225 | 0.83 | ELANE (0.58) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL3278923 | 0.81 | ELANE (0.55) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL3272136 | 0.79 | ELANE (0.54) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL17866722 | 0.78 | JUN (0.56) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL5968219 | 0.77 | ESR1 (0.77) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL29390162 | 0.77 | ESR1 (0.77) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL23522401 | 0.72 | EGFR (0.57) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL20515152 | 0.72 | EGFR (0.57) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL20515153 | 0.72 | EGFR (0.57) | ELANEALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL29359669 | 0.72 | EGFR (0.57) | ELANEALDH1A1MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146032-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2026-05-28 | — | — | US | disclosed |
| US-12508234-B2 | Pharmaceutical formulation of odevixibat | ALBIREO AB (SE) | 2025-12-30 | — | — | US | disclosed |
| US-20250333390-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2025-10-30 | — | — | US | disclosed |
| US-20250326728-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2025-10-23 | — | — | US | disclosed |
| EP-4347575-B1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2025-07-23 | — | — | EP | disclosed |
| US-12365658-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | ALBIREO AB (SE) | 2025-07-22 | — | — | US | disclosed |
| US-20250100983-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2025-03-27 | — | — | US | disclosed |
| US-12202809-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | ALBIREO AB (SE) | 2025-01-21 | — | — | US | disclosed |
| US-20250019353-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2025-01-16 | — | — | US | disclosed |
| US-20250019354-A1 | Crystal Modifications of Odevixibat | ALBIREO AB (SE) | 2025-01-16 | — | — | US | disclosed |
| US-20220162176-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2022-05-26 | — | — | US | disclosed |
| US-11306064-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | ALBIREO AB (SE) | 2022-04-19 | — | — | US | disclosed |
| US-11267794-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | ALBIREO AB (SE) | 2022-03-08 | — | — | US | disclosed |
| US-20220041567-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2022-02-10 | — | — | US | disclosed |
| US-20220041568-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2022-02-10 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| US-7691418-B2 | Composition for inhibiting or preventing the formation of a biofilm | OYSTERSHELL NV (BE) | 2010-04-06 | — | — | US | disclosed |
| US-20070258913-A1 | Composition for Inhibiting or Preventing the Formation of a Biofilm | OYSTERSHELL NV (BE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11267794-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | SLC10A1, SLC10A2, ABCB11 | ELANE 3885/4885ALDH1A1 1005/4885MAPT 385/4885 |
| US-20250333390-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | ELANE 3902/4885ALDH1A1 688/4885MAPT 443/4885 |
| US-20220041568-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | ELANE 3895/4885ALDH1A1 675/4885MAPT 467/4885 |
| US-12508234-B2 | Pharmaceutical formulation of odevixibat | SLC10A1, ABCB11, SLC10A2 | ELANE 2538/4885ALDH1A1 2794/4885MAPT 891/4885 |
| US-11306064-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | SLC10A1, SLC10A2, ABCB11 | ELANE 3902/4885ALDH1A1 688/4885MAPT 443/4885 |
| US-20250326728-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | ELANE 4495/4885ALDH1A1 580/4885MAPT 420/4885 |
| US-20220162176-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | ELANE 3885/4885ALDH1A1 1005/4885MAPT 385/4885 |
| US-20070258913-A1 | Composition for Inhibiting or Preventing the Formation of a Biofilm | NQO2, NFKBIA, CROCC | ELANE 208/4885ALDH1A1 2205/4885MAPT 4695/4885 |
| US-20250019353-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | ELANE 3902/4885ALDH1A1 688/4885MAPT 443/4885 |
| US-20250100983-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | ELANE 3885/4885ALDH1A1 1005/4885MAPT 385/4885 |
| US-12365658-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | SLC10A1, SLC10A2, ABCB11 | ELANE 3902/4885ALDH1A1 688/4885MAPT 443/4885 |
| US-20220041567-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | ELANE 3885/4885ALDH1A1 1005/4885MAPT 385/4885 |
| US-20250019354-A1 | Crystal Modifications of Odevixibat | OR10J3, SULT1E1, OPRD1 | ELANE 4798/4885ALDH1A1 863/4885MAPT 20/4885 |
| US-12202809-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | SLC10A1, SLC10A2, ABCB11 | ELANE 3902/4885ALDH1A1 688/4885MAPT 443/4885 |
| US-20260146032-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A2, SLC10A1, SLC5A2 | ELANE 2952/4885ALDH1A1 1583/4885MAPT 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.