Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786691 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1GRIK1KISS1RCA2 | |
| SCHEMBL11554888 | 0.83 | CACNA2D1 (0.36) | ALDH1A1TDP1GRIK1 | |
| SCHEMBL22500794 | 0.83 | CACNA2D1 (0.36) | ALDH1A1TDP1GRIK1 | |
| SCHEMBL22500795 | 0.83 | CACNA2D1 (0.36) | ALDH1A1TDP1GRIK1 | |
| SCHEMBL4064329 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1GRIK1KISS1R | |
| SCHEMBL10290198 | 0.78 | CHRNB2 (0.33) | KISS1R | |
| SCHEMBL11553513 | 0.78 | CHRNB2 (0.35) | — | |
| SCHEMBL10291261 | 0.78 | CHRNB2 (0.33) | KISS1R | |
| SCHEMBL10290201 | 0.78 | CHRNB2 (0.33) | KISS1R | |
| SCHEMBL1783174 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TDP1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885TDP1 3995/4885GRIK1 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.