Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.53 |
| ▸ | SI | P14410 | 2/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341491 | 0.79 | CYP3A4 (0.50) | CYP3A4ALDH1A1GAAMCL1KDM4E | |
| SCHEMBL30616018 | 0.76 | CYP3A4 (0.57) | CYP3A4ALDH1A1GAAMCL1KDM4E | |
| SCHEMBL5336436 | 0.74 | CYP3A4 (0.45) | CYP3A4ALDH1A1GAAMCL1KDM4E | |
| SCHEMBL28899964 | 0.74 | CLK2 (0.64) | CYP3A4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL29459740 | 0.71 | ALDH1A1 (0.51) | CYP3A4ALDH1A1GAAMCL1KDM4E | |
| SCHEMBL5341413 | 0.71 | CYP3A4 (0.46) | CYP3A4ALDH1A1GAAMCL1KDM4E | |
| SCHEMBL27426246 | 0.71 | MAOA (0.67) | CYP3A4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL5118377 | 0.70 | ALDH1A1 (0.86) | CYP3A4ALDH1A1GAAMCL1KDM4E | |
| SCHEMBL5337247 | 0.70 | ALDH1A1 (0.69) | CYP3A4ALDH1A1GAAMCL1KDM4E | |
| SCHEMBL31465207 | 0.70 | MAOA (0.66) | GAAKDM4EMAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |