Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608325 | 1.00 | TDP1 (0.54) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23100892 | 0.98 | RAB9A (0.55) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13909710 | 0.98 | RAB9A (0.55) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL15923240 | 0.92 | TDP1 (0.58) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29384887 | 0.92 | TDP1 (0.58) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29263682 | 0.92 | TDP1 (0.58) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12661123 | 0.92 | TDP1 (0.58) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13256453 | 0.92 | TDP1 (0.58) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13256445 | 0.92 | TDP1 (0.58) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19344706 | 0.92 | MAOB (0.50) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772540-B2 | Thermal responsive molecule | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20110124916-A1 | THERMAL RESPONSIVE MOLECULE | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124916-A1 | THERMAL RESPONSIVE MOLECULE | HEATR1, HEATR6, HSPH1 | TDP1 1136/4885L3MBTL1 92/4885MAPT 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.