SCHEMBL17867304

SCHEMBL17867304

CCC(=O)C=CC=CC(C)C(O)CC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
OXER1 Q8TDS5 3/20 0.33
GAPDH P04406 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
IAPP P10997 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867303 1.00 ACHE (0.35) ACHEBACE1OXER1GAPDHALDH1A1
SCHEMBL16431536 0.83 ACHE (0.51) ACHEBACE1OXER1GAPDHALDH1A1
SCHEMBL16431537 0.83 ACHE (0.51) ACHEBACE1OXER1GAPDHALDH1A1
SCHEMBL16431525 0.81 ACHE (0.36) ACHEBACE1OXER1
SCHEMBL16431527 0.81 ACHE (0.36) ACHEBACE1OXER1
SCHEMBL13611714 0.76 ALDH1A1 (0.36) ACHEBACE1OXER1ALDH1A1TSHR
SCHEMBL1784742 0.74 GAPDH (0.58) GAPDHTSHR
SCHEMBL5500609 0.74 GAPDH (0.58) GAPDHTSHR
SCHEMBL1784744 0.74 GAPDH (0.58) GAPDHTSHR
SCHEMBL16431404 0.74 FOLH1 (0.34) ACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed