SCHEMBL17867396

SCHEMBL17867396

CCCC(O)=CC(=O)c1c(C)cc2c(c1O)C(=O)c1c(O)cccc1C2=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC37A4 O43826 3/20 0.51
JUN P05412 1/20 0.50
ELANE P08246 8/20 0.49
CTSG P08311 7/20 0.49
TCF4 P15884 1/20 0.48
CTNNB1 P35222 1/20 0.48
ITGA2 P17301 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP3A4 P08684 2/20 0.46
RECQL P46063 2/20 0.46
MAPK1 P28482 2/20 0.46
USP2 O75604 1/20 0.46
BRCA1 P38398 1/20 0.46
FTO Q9C0B1 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867394 1.00 SLC37A4 (0.51) SLC37A4JUNELANECTSGTCF4
SCHEMBL29885560 0.84 TCF4 (0.60) SLC37A4JUNELANECTSGTCF4
SCHEMBL17867433 0.80 ELANE (0.62) SLC37A4JUNELANECTSGITGA2
SCHEMBL16432557 0.78 ELANE (0.62) SLC37A4JUNELANECTSGITGA2
SCHEMBL3192604 0.73 ELANE (0.71) SLC37A4ELANECTSGALDH1A1MAPT
SCHEMBL31238107 0.73 ELANE (0.71) SLC37A4ELANECTSGALDH1A1MAPT
SCHEMBL16431803 0.73 ELANE (0.62) SLC37A4JUNELANECTSGTCF4
SCHEMBL16225947 0.70 ELANE (0.54) SLC37A4ELANECTSGALDH1A1MAPT
SCHEMBL16225945 0.70 ELANE (0.54) SLC37A4ELANECTSGALDH1A1MAPT
SCHEMBL16225941 0.70 ELANE (0.54) SLC37A4ELANECTSGALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed