SCHEMBL1786858

SCHEMBL1786858

CC(C)(C)C(CC(OC(=O)c1ccccc1)C(C)(C)C)OC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
TSHR P16473 3/20 0.52
TP53 P04637 1/20 0.52
ALDH1A1 P00352 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C19 P33261 1/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
LMNA P02545 4/20 0.45
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
F2 P00734 1/20 0.45
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16045662 0.91 MEN1 (0.54) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL27503340 0.90 MEN1 (0.57) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL569453 0.90 MEN1 (0.57) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL1073178 0.88 MEN1 (0.54) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL16045943 0.86 MEN1 (0.50) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL16048138 0.86 KMT2A (0.50) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL9929403 0.85 MEN1 (0.58) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL15933406 0.83 KMT2A (0.50) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL31465102 0.82 KMT2A (0.56) MEN1KMT2ATSHRTP53ALDH1A1
SCHEMBL16044089 0.82 MEN1 (0.46) MEN1KMT2ATSHRTP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754801-B Solid catalyst for preparing olefin polymer and solid catalyst system 中国石油化工股份有限公司 2023-02-28 CN claimed
CN-113754803-B Catalyst system and application thereof as catalyst for olefin polymerization 中国石油化工股份有限公司 2023-02-24 CN claimed
CN-114426599-A Catalyst component for preparing polyolefin, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2022-05-03 CN claimed
CN-113754803-A Catalyst system and application thereof as catalyst for olefin polymerization 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-113754801-A Solid catalyst for preparing olefin polymer and solid catalyst system 中国石油化工股份有限公司 2021-12-07 CN claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
CN-104558293-B Catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2017-02-15 CN claimed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US claimed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US claimed
US-11840508-B2 Catalyst system for olefin polymerization and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-12-12 US disclosed
CN-113754802-B Catalyst system for olefin polymerization reaction and prepolymerization catalyst composition 中国石油化工股份有限公司 2023-03-31 CN disclosed
CN-112300311-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2023-03-28 CN disclosed
CN-113754801-B Solid catalyst for preparing olefin polymer and solid catalyst system 中国石油化工股份有限公司 2023-02-28 CN disclosed
CN-113754803-B Catalyst system and application thereof as catalyst for olefin polymerization 中国石油化工股份有限公司 2023-02-24 CN disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840508-B2 Catalyst system for olefin polymerization and use thereof SQSTM1, SAMM50, HPD MEN1 3698/4885KMT2A 3087/4885TSHR 4688/4885
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 MEN1 3520/4885KMT2A 2151/4885TSHR 921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.