SCHEMBL9929403

SCHEMBL9929403

COCC(OC(=O)c1ccccc1)C(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 3/20 0.47
TP53 P04637 1/20 0.47
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
ALDH1A1 P00352 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
LMNA P02545 3/20 0.45
HSD17B10 Q99714 1/20 0.45
PRKCA P17252 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14974547 0.86 TDP1 (0.49) MEN1KMT2AADRB2ADRB1ADRB3
SCHEMBL1786858 0.85 MEN1 (0.62) MEN1KMT2ATSHRTP53ADRB2
SCHEMBL14974093 0.84 ALDH1A1 (0.43) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL10062943 0.84 ADRB2 (0.50) MEN1KMT2AADRB2ADRB1ADRB3
SCHEMBL14335513 0.83 HPGD (0.53) MEN1KMT2AALDH1A1CYP2C19RAB9A
SCHEMBL14974822 0.83 MEN1 (0.45) MEN1KMT2ATSHRTP53TDP1
SCHEMBL31465102 0.81 KMT2A (0.56) MEN1KMT2ATSHRTP53ADRB2
SCHEMBL14974848 0.81 CYP4A11 (0.46) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL14974677 0.80 ADRB2 (0.48) MEN1KMT2ATSHRADRB2ADRB1
SCHEMBL14975364 0.80 CYP4F2 (0.47) MEN1KMT2AALDH1A1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434796-B2 Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same W. R. GRACE & CO.-CONN. (US) 2016-09-06 US disclosed
US-9434796-B2 Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same W. R. GRACE & CO.-CONN. (US) 2016-09-06 US disclosed
US-9434796-B2 Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same W. R. GRACE & CO.-CONN. (US) 2016-09-06 US disclosed
US-9315592-B2 Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product W. R. GRACE & CO.-CONN. (US) 2016-04-19 US disclosed
US-9315592-B2 Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product W. R. GRACE & CO.-CONN. (US) 2016-04-19 US disclosed
US-9315592-B2 Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product W. R. GRACE & CO.-CONN. (US) 2016-04-19 US disclosed
US-8604146-B2 Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-10 US disclosed
US-20130289231-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W. R. GRACE & CO.-CONN. 2013-10-31 US disclosed
US-20130289231-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W. R. GRACE & CO.-CONN. 2013-10-31 US disclosed
US-20130289231-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W. R. GRACE & CO.-CONN. 2013-10-31 US disclosed
US-20130225398-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-29 US disclosed
US-20130225398-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-29 US disclosed
US-20130225398-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-29 US disclosed
WO-2012087531-A1 CATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND POLYMER FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO disclosed
US-20120157642-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W.R. GRACE & CO.-CONN. 2012-06-21 US disclosed
US-20120157295-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product W. R. GRACE & CO. - CONN. 2012-06-21 US disclosed
US-20120157642-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W.R. GRACE & CO.-CONN. 2012-06-21 US disclosed
US-20120157295-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product W. R. GRACE & CO. - CONN. 2012-06-21 US disclosed
US-20120157295-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product W. R. GRACE & CO. - CONN. 2012-06-21 US disclosed
US-20120157642-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W.R. GRACE & CO.-CONN. 2012-06-21 US disclosed