Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.46 |
| ▸ | KLK1 | P06870 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786875 | 1.00 | KLKB1 (0.46) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1787879 | 1.00 | KLKB1 (0.46) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1789392 | 0.90 | ALDH1A1 (0.49) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1788393 | 0.89 | HRH3 (0.49) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1787839 | 0.89 | HRH3 (0.49) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1787838 | 0.89 | HRH3 (0.49) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1786906 | 0.82 | HRH3 (0.49) | NAMPTPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1792073 | 0.82 | HRH3 (0.50) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1787761 | 0.82 | ADRA1A (0.52) | KLKB1KLK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1790222 | 0.82 | NAMPT (0.43) | CXCR3DGAT2NAMPTPRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | HRH4, HRH3, HRH2 | KLKB1 3739/4885KLK1 3121/4885RAB9A 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.