Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31513977 | 0.82 | HTR2C (0.38) | HTR2CHTR2AHTR2BPNMTAHR | |
| SCHEMBL1896564 | 0.82 | HTR2C (0.38) | HTR2CHTR2AHTR2BPNMTAHR | |
| SCHEMBL6832707 | 0.78 | HTR2A (0.35) | HTR2CHTR2AHTR2BPNMTCMA1 | |
| SCHEMBL924413 | 0.77 | CYP1A2 (0.35) | HTR2BMETAP1TP53CA1CA2 | |
| SCHEMBL9629684 | 0.76 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL275807 | 0.74 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL3755892 | 0.74 | ESR1 (0.38) | HTR2CHTR2AHTR2BCYP3A4ALOX15 | |
| SCHEMBL2730845 | 0.73 | MAPT (0.36) | CA1CA2CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL2965930 | 0.73 | TRPA1 (0.37) | HTR2CHTR2AHTR2BPNMTCMA1 | |
| SCHEMBL275808 | 0.73 | PBRM1 (0.36) | CA1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | claimed |
| CN-1653021-A | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | CN | claimed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | claimed |
| EP-4392410-A1 | TRANSCRIPTION FACTOR BRN2 INHIBITORY COMPOUNDS FOR USE AS THERAPEUTICS | The University of British Columbia (CA) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023023853-A1 | TRANSCRIPTION FACTOR BRN2 INHIBITORY COMPOUNDS FOR USE AS THERAPEUTICS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-03-02 | — | — | WO | disclosed |
| CN-112105654-A | Curable resin mixture, curable resin composition, and cured product thereof | 日本化药株式会社 | 2020-12-18 | — | — | CN | disclosed |
| WO-2020252205-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | Praxis Biotech LLC (US) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020031935-A1 | CURABLE RESIN MIXTURE, CURABLE RESIN COMPOSITION, AND CURED PRODUCT | 日本化薬株式会社 | 2020-02-13 | — | — | WO | disclosed |
| CN-208980610-U | 5- chlorine indone process units | 宿迁市科莱博生物化学有限公司 | 2019-06-14 | — | — | CN | disclosed |
| US-9573939-B2 | Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases | MERCK SHARP & DOHME CORP. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9540400-B2 | Compounds as diacylglycerol acyltransferase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-01-10 | — | — | US | disclosed |
| WO-2005058836-A1 | INSECTICIDAL SPIROINDANE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
| US-6087292-A | Metallocene catalysts comprising indenyl ligands substituted with electronegative groups | TANGOR GMBH (DE) | 2000-07-11 | — | — | US | disclosed |
| US-5763542-A | Process for the preparation of an olefin polymer using specific metallocenes | TARGOR GMBH (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0505972-B1 | Process for producing styrenic copolymer | IDEMITSU KOSAN CO (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5504232-A | Process for the preparation of an olefin polymer using specific metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0505972-A2 | Process for producing styrenic copolymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | INTS9, CYP1A2, INF2 | HTR2C 3399/4885HTR2A 3428/4885HTR2B 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.