SCHEMBL9629684

SCHEMBL9629684

C1=Cc2cc(-c3ccc4c(c3)C=CC4)ccc2C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6537108 0.91 HSD17B1 (0.37) CA1CA2
SCHEMBL5158791 0.89 TYRO3 (0.40) CA1CA2
SCHEMBL22568840 0.82 CA1 (0.47) CA1CA2
SCHEMBL275807 0.78 CA1 (0.33) CA1CA2
SCHEMBL924411 0.76 CA1 (0.32) CA1CA2
SCHEMBL2730845 0.76 MAPT (0.36) CA1CA2
SCHEMBL17068939 0.76 ADRA2A (0.33) CA1CA2
SCHEMBL2965930 0.76 TRPA1 (0.37) CA1CA2
SCHEMBL1786889 0.76 HTR2C (0.38) CA1CA2
SCHEMBL819543 0.76 ADRA2A (0.33) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116685313-A Indanyl-containing carboxylic acid compounds for the treatment of neurodegenerative diseases 细胞基因公司 2023-09-01 CN disclosed
US-5157182-A Conversion of ortho-ethyltoluene to indene AMOCO CORPORATION (US) 1992-10-20 US disclosed