Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 3/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15229791 | 0.72 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DMPO | |
| SCHEMBL16652006 | 0.70 | ADORA2A (0.36) | ALDH1A1CSNK2A1 | |
| SCHEMBL9725356 | 0.70 | CCR4 (0.43) | MPOHAVCR2DAOSMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL9725475 | 0.69 | CCR4 (0.42) | MPOHAVCR2DAOSMN1; SMN2ALDH1A1 | |
| SCHEMBL7615724 | 0.69 | TSHR (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9725374 | 0.68 | DAO (0.36) | PDE4APDE4BPDE4CPDE4DMPO | |
| SCHEMBL9725387 | 0.68 | DAO (0.36) | PDE4APDE4BPDE4CPDE4DMPO | |
| SCHEMBL29099240 | 0.68 | DAO (0.47) | PDE4APDE4BPDE4CPDE4DMPO | |
| Hydrochloric Acid SCHEMBL9725534 | 0.67 | DAO (0.35) | PDE4APDE4BPDE4CPDE4DMPO | |
| Hydrochloric Acid SCHEMBL9725460 | 0.67 | DAO (0.35) | PDE4APDE4BPDE4CPDE4DMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |